The Neuroimaging and Biotechnology Lab (NIBL)


The Neuroimaging and Biotechnology Lab (NIBL)

The Neuroimaging and Biotechnology Lab (NIBL) at the University of Utah Health Department of Radiology and Imaging Sciences is committed to advancing research on brain disorders, including Alzheimer’s disease, dementia, traumatic brain injury, and age-related cognitive decline.

We are currently investigating promising therapeutic strategies for Alzheimer’s disease, a devastating condition with no effective treatments. Early studies in animal models show that paclitaxel, a well known chemotherapy drug, significantly improves memory loss and other symptoms associated with Alzheimer’s. Paclitaxel works by stabilizing microtubules, which help maintain cell structure and transport essential molecules. In brain cells affected by Alzheimer’s, this stabilization helps preserve cellular function and slow disease progression.

To bring this research closer to clinical application, we are developing advanced drug delivery systems that can bypass the blood-brain barrier—a protective shield that prevents most medications from reaching brain tissue. By linking paclitaxel to specialized peptides that target brain-specific receptors, we aim to deliver the drug directly to affected cells.

This approach holds potential not only for Alzheimer’s disease but also for other neurodegenerative conditions such as Parkinson’s disease, multiple sclerosis, ALS, and traumatic brain injuries.
Your support helps accelerate the development of these innovative therapies and brings hope to millions affected by these debilitating diseases. Together, we can make a meaningful impact on brain health and the future of neurodegenerative treatment.

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Because of you, we can support more students.

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